Publications in Nanomedicine

1.Functionalization

  • Figuereido, I., Paiotta, A., Dal Magro, R., Tinelli, F., Corti, R., Re, F., Cassina, V., Caneva, E., Nicotra, F., Russo, L.  “A new approach for glyco-functionalization of collagen-based biomaterials” International Journal of Molecular Sciences Volume 20, Issue 7, 1 April 2019, Article number 1747
  • Gregori, M., Orlando, A., Re, F., Sesana, S., Nardo, L., Salerno, D., Mantegazza, F., Salvati, E., Zito, A., Malavasi, F., Masserini, M., Cazzaniga, E. “Novel Antitransferrin Receptor Antibodies Improve the Blood-Brain Barrier Crossing Efficacy of Immunoliposomes” Journal of Pharmaceutical Sciences, 105, 276-283, (2016)
  • Gregori, M., Bertani, D., Cazzaniga, E., Orlando, A., Mauri, M., Bianchi, A., Re, F., Sesana, S., Minniti, S., Francolini, M., Cagnotto, A., Salmona, M., Nardo, L., Salerno, D.,  Mantegazza, F., Masserini, M., Simonutti, R. “Investigation of Functionalized Poly(N,N-dimethylacrylamide)-block-polystyrene Nanoparticles As Novel Drug Delivery System to Overcome the Blood-Brain Barrier in Vitro” Macromolecular Bioscience, 15, 1687-1697, (2015)
  • Rizzi, M. Braschi, M. Colombo,N. Vaiana, G. Tibolla, G. D. Norata, A. L. Catapano,S. Romeo, D. Prosperi “Novel Biotinylated Bile Acid Amphiphiles: Micellar Aggregates Formation and Interaction with Hepatocytes” Org. Biomol. Chem., 2011, in press. DOI:10.1039/C0OB00878H.
  • Occhipinti, P. Verderio, A. Natalello, E. Galbiati, M. Colombo, S. Mazzucchelli, P. Tortora, S. M. Doglia, D. Prosperi “Investigating the structural biofunctionality of antibodies conjugated to magnetic Nanoparticles” Nanoscale, 2011, Epub (DOI: 10.1039/C0NR00436G).
  • Prosperi, L. Polito, C. Morasso, D. Monti “Biofunctionalization of spherical and anisotropic bimetallic nanomaterials”, Mixed Metal Nanomaterials, 2010, Vol. 3, pp. 197-240. 10 volume series of books on “Nanomaterials  for the Life Sciences”, Ed. C. S. S. R. Kumar, Wiley-VCH Verlag GmbH & Co. KGaA,  Weinheim.
  • Morasso, M. Colombo, S. Ronchi, L. Polito, S. Mazzucchelli, D. Monti, M. Buscaglia, T. Bellini,D. Prosperi “Towards a universal method for the stable and clean functionalization of inert perfluoropolymer nanoparticles: exploitingphotopolymerizable amphiphilic diacetylenes”  Adv. Funct. Mater., 2010, 20, 3932-3940
  • Polito, D. Monti, E. Caneva, E. Delnevo, G. Russo, D. Prosperi “One-step bioengineering of magnetic nanoparticles via a surface diazo transfer/azide-alkyne click reaction sequence” Chem. Commun., 2008, 621-623 Paper also published in Highlights inChemical Biology, 2008, issue 3
  • Polito, M. Colombo, D. Monti, S. Melato, E. Caneva, D. Prosperi “Resolving the structure of ligands bound to the surface of superparamagnetic iron oxide nanoparticles by HRMAS NMR Spectroscopy” Am. Chem. Soc., 2008, 130, 12712-12724.
  • Ronchi, M. Colombo, P. Verderio, S. Mazzucchelli, F. Corsi, C. De Palma, R. Allevi, E. Clementi, D. Prosperi “Magnetofluorescent nanoparticles for bimodal detection of breast cancer cells” AIP Conf. Proc., 2010, 1275, 102-105.
  • Corsi, D. Prosperi “Molecular nanoclinics: dream or reality?” Pharmacol. Res., 2010, 62, 55-56.
  • El-Boubbou, D. Zhu, C. Vasileiou, B. Borhan, D. Prosperi, W. Li, X. Huang “Magnetic glyco-nanoparticles: an efficient tool for cancer cell detection, differentiation and profiling based on carbohydrate binding via magnetic resonance imaging” Am. Chem. Soc., 2010, 132, 4490-4499

2. Therapy

  • Formicola, B., Dal Magro, R., Cox, A., Masserini, M., Re, F. “Nanomedicine for Alzheimer disease”  Journal of Biomedical Nanotechnology in press
  • Cox, A., Vinciguerra, D., Re, F., Dal Magro, R., Mura, S., Masserini, M., Couvreur, P., Nicolas, J. “Protein-Functionalized Nanoparticles Derived from End-Functional Polymers and Polymer Prodrugs for Crossing the Blood-Brain Barrier” Eur J Pharm Biopharm. 2019 Jun 6.
  • Dal Magro, R., Simonelli, S., Cox, A., Formicola, B., Corti, R., Cassina, V., Nardo, L., Mantegazza, F., Salerno, D., Grasso, G., Deriu, M.A., Danani, A., Calabresi, L., Re, F. “The Extent of Human Apolipoprotein A-I Lipidation Strongly Affects the β-Amyloid Efflux Across the Blood-Brain Barrier in vitro” Front Neurosci. 2019 May 16;13:419.
  • Andrieu, J., Re, F., Russo, L., Nicotra, F.  “Phage-displayed peptides targeting specific tissues and organs” (Review) Journal of Drug Targeting Volume 27, Issue 5-6, 3 July 2019, Pages 555-565
  • Cox, A., Andreozzi, P., Dal Magro, R., Fiordaliso, F., Corbelli, A., Talamini, L., Chinello, C., Raimondo, F., Magni, F., Tringali, M., Krol, S., Jacob Silva, P., Stellacci, F., Masserini, M., Re, F.“Evolution of Nanoparticle Protein Corona across the Blood-Brain Barrier” ACS Nano Volume 12, Issue 7, 24 July 2018, Pages 7292-7300
  • Binda, A., Panariti, A., Barbuti, A., Murano, C., Dal Magro, R.D., Masserini, M., Re, F., Rivolta, I. “Modulation of the intrinsic neuronal excitability by multifunctional liposomes tailored for the treatment of Alzheimer’s disease” International Journal of Nanomedicine Volume 13, 2018, Pages 4059-4071
  • Ugolini GF, Occhetta P, Saccani A, Re F, Krol S, Rasponi M, Redaelli A. Design and validation of a microfluidic device for blood–brain barrier monitoring and transport studies Micromech. Microeng. 2018, 28: 044001 (9pp)
  • Dal Magro R, Cox A, Zambelli V, Mancini S, Masserini M, Re F. The ability of liposomes, tailored for BBB targeting, to reach the brain is dramatically affected by the disease state. Nanomedicine (Lond), 2018 Jan 29.
  • Carradori D, Balducci C, Re F, Brambilla D, Le Droumaguet B, Flores O, Gaudin A, Mura S, Forloni G, Ordoñez-Gutierrez L, Wandosell F, Masserini M, Couvreur P, Nicolas J, Andrieux K. Antibody-Functionalized Polymer Nanoparticle Leading to Memory Recovery in Alzheimer’s Disease-like Transgenic Mouse Model. Nanomedicine. 2017; 17: 30584-1.
  • Mancini S, Balducci C, Micotti E, Tolomeo D, Forloni G, Masserini M, Re F. Multifunctional liposomes delay phenotype progression and prevent memory impairment in a presymptomatic stage mouse model of Alzheimer disease. J Control Release 2017;258:121-129.
  • Conti E, Gregori M, Radice I, Da Re F, Grana D, Re F, Salvati E, Masserini M, Ferrarese C, Zoia CP, Tremolizzo L. Multifunctional liposomes interact with Abeta in human biological fluids: Therapeutic implications for Alzheimer’s disease. Neurochem Int. 2017; pii: S0197-0186(16)30345-X.
  • Orlando A, Cazzaniga E, Tringali M, Gullo F, Becchetti A, Minniti S, Taraballi F, Tasciotti E, Re F. Mesoporous silica nanoparticles trigger mitophagy in endothelial cells and perturb neuronal network activity in a size- and time-dependent manner. Int J Nanomedicine 2017;12:3547-3559.
  • Dal Magro R, Ornaghi F, Cambianica I, Beretta S, Re F, Musicanti C, Rigolio R, Donzelli E, Canta A, Ballarini E, Cavaletti G, Gasco P, Sancini G. ApoE-modified solid lipid nanoparticles: A feasible strategy to cross the blood-brain barrier. J Control Release. 2017;249:103-110.
  • Gregori M, Taylor M, Salvati E, Re F, Mancini S, Balducci C, Forloni G, Zambelli V, Sesana S, Michael M, Michail C, Tinker-Mill C, Kolosov O, Scherer M, Harris S, Fullwood NJ, Masserini M, Allsop D. Retro-inverso peptide inhibitor nanoparticles as potent inhibitors of aggregation of the Alzheimer’s Aβ peptide. Nanomedicine. 2017;13(2):723-732.
  • Sancini G, Dal Magro R, Ornaghi F, Balducci C, Forloni G, Gobbi M, Salmona M, Re F. Pulmonary administration of functionalized nanoparticles significantly reduces beta-amyloid in the brain of an Alzheimer’s disease murine model. Nano Research 2016; 9 (7): 2190-2201
  • Nardo L, Re F, Brioschi S, Cazzaniga E, Orlando A, Minniti S, Lamperti M, Gregori M, Cassina V, Brogioli D, Salerno D, Mantegazza F. Fluorimetric detection of the earliest events in amyloid β oligomerization and its inhibition by pharmacologically active liposomes. Biochim Biophys Acta 2016;1860(4):746-56
  • Gregori M, Orlando A, Re F, Sesana S, Nardo L, Salerno D, Mantegazza F, Salvati E, Zito A, Malavasi F, Masserini M, Cazzaniga E. Novel Antitransferrin Receptor Antibodies Improve the Blood-Brain Barrier Crossing Efficacy of Immunoliposomes. J Pharm Sci 2016;105(1):276-283
  • Mancini S, Minniti S, Gregori M, Sancini G, Cagnotto A, Couraud PO, Ordóñez-Gutiérrez L, Wandosell F, Salmona M, Re F. The hunt for brain Aβ oligomers by peripherally circulating multi-functional nanoparticles: Potential therapeutic approach for Alzheimer disease. Nanomedicine 2016;12(1):43-52
  • Gregori M, Bertani D, Cazzaniga E, Orlando A, Mauri M, Bianchi A, Re F, Sesana S, Minniti S, Francolini M, Cagnotto A, Salmona M, Nardo L, Salerno D, Mantegazza F, Masserini M, Simonutti R. Investigation of Functionalized Poly(N,N-dimethylacrylamide)-block-polystyrene Nanoparticles As Novel Drug Delivery System to Overcome the Blood-Brain Barrier In Vitro. Macromol Biosci 2015;15(12):1687-97
  • Ordóñez-Gutiérrez L, Re F, Bereczki E, Ioja E, Gregori M, Andersen AJ, Antón M, Moghimi SM, Pei JJ, Masserini M, Wandosell F. Repeated intraperitoneal injections of liposomes containing phosphatidic acid and cardiolipin reduce amyloid-β levels in APP/PS1 transgenic mice. Nanomedicine 2015;11(2):421-30
  • Balducci C, Mancini S, Minniti S, La Vitola P, Zotti M, Sancini G, Mauri M, Cagnotto A, Colombo L, Salmona M, Snellman A, Haaparanta-Solin M, Forloni G, Masserini M, Re F. Multi-functional liposomes reduce brain β-amyloid burden and ameliorate memory impairment in Alzheimer’s disease mouse models. J Neurosci 2014;34(42):14022-31
  • Bana L, Minniti S, Salvati E, Sesana S, Zambelli V, Cagnotto A, Orlando A, Cazzaniga E, Zwart R, Scheper W, Masserini M, Re F. Liposomes bi-functionalized with phosphatidic acid and an ApoE-derived peptide affect Aβ aggregation features and cross the blood-brain-barrier: Implications for therapy of Alzheimer disease. Nanomedicine 2014;10(7):1583-90
  • Sancini G, Gregori M, Salvati E, Cambianica I, Re F, Ornaghi F, Canovi M, Fracasso C, Cagnotto A, Colombo M, Zona C, Gobbi M, Salmona M, La Ferla B, Nicotra F, Masserini M. Functionalization with TAT-peptide enhances blood-brain barrier crossing in vitro of nanoliposomes carrying a curcumin-derivative to bind amyloid-β peptide. Journal of Nanomedicine & Nanotechnology 2013;4:1-8
  • Salvati E, Re F, Sesana S, Cambianica I, Sancini G, Masserini M, Gregori M. Liposomes functionalized to overcome the blood-brain barrier and to target amyloid-β peptide: the chemical design affects the permeability across an in vitro model. International Journal of Nanomedicine 2013;8:1749-1758
  • Orlando A, Re F, Sesana S, Rivolta I, Panariti A, Brambilla D, Nicolas J, Couvreur P, Andrieux K, Masserini M, Cazzaniga E. Effect of nanoparticles binding β-amyloid peptide on nitric oxide production by cultured endothelial cells and macrophages. International Journal of Nanomedicine 2013;8:1335-1347
  • Canovi M, Lucchetti J, Stravalaci M, Re F, Moscatelli D, Bigini P, Salmona M, Gobbi M. Applications of Surface Plasmon Resonance (SPR) for the characterization of nanoparticles developed for biomedical purposes. Sensors 2012;12(12):16420-16432
  • Re F, Gregori M, Masserini M. Nanotechnology for neurodegenerative disorders. Maturitas 2012;73(1):45-51
  • Re F, Gregori M, Masserini M. Nanotechnology for neurodegenerative disorders. Nanomedicine 2012; 8(1):S51-S58
  • Salvati E, Masserini M, Sesana S, Sonnino S, Re F, Gregori M. Liposomes functionalized with GT1b ganglioside with high affinity for amyloid beta-peptide. Journal of Alzheimer’s Disease 2012;29(SUPPL. 1):33-36 ISSN: 0022-3727 DOI: 10.1088/0022-3727/45/7/07300
  • Taylor M, Moore S, Mourtas S, Niarakis A, Re F, Zona C, la Ferla B, Nicotra F, Masserini ME, Antimisiaris S, Gregori M, Allsop D. Effect of curcumin-associated and lipid ligand functionalised nanoliposomes on aggregation of the Alzheimer’s Aβ peptide. Nanomedicine 2011; 7: 541-550
  • Bereczki E, Re F, Masserini ME, Winblad B, Pei JJ. Liposomes functionalized with acidic lipids rescue Aβ-induced toxicity in murine neuroblastoma cells. International Journal of Nanomedicine 2011;7:560-571
  • Re F, Cambianica IN, Zona C, Sesana MS, Gregori M, Rigolio R, La Ferla B, Nicotra F, Forloni G, Cagnotto A, Salmona M, Masserini ME, Sancini GA. Functionalization of liposomes with ApoE-derived peptides at different density affects cellular uptake and drug transport across a blood-brain barrier model. Nanomedicine 2011;7:551-559
  • Canovi M, Markoutsa E, Lazar AN, Pampalakis G, Clemente C, Re F, Sesana MS, Masserini ME, Salmona M, Duyckaerts C, Flores O, Gobbi M, Antimisiaris SG. The binding affinity of anti-Aβ1-42 MAb-decorated nanoliposomes to Aβ1-42 peptides in vitro and to amyloid deposits in post-mortem tissue. Biomaterials 2011;32(23):5489-5497
  • Cazzaniga E, Bulbarelli A, Lonati ER, Orlando A, Re F, Gregori M, Masserini M. Abeta peptide toxicity is reduced after treatments decreasing phosphatidylethanolamine content in differentiated neuroblastoma cells. Neurochemical Research 2011;36(5):863-869
  • Re F, Cambianica IN, Sesana MS, Salvati E, Cagnotto A, Salmona M, Couraud PO, Moghimi SM, Masserini M, Sancini G. Functionalization with ApoE-derived peptides enhances the interaction with brain capillary endothelial cells of nanoliposomes binding amyloid-beta peptide. Journal of Biotechnology 2011;156(4):341-346
  • Gobbi M, Re F*, Canovi M, Beeg M, Gregori M, Sesana MS, Sonnino S, Brogioli DC, Musicanti C, Gasco P, Salmona M, Masserini M. Lipid-based nanoparticles with high binding affinity for amyloid-b1-42 peptide. Biomaterials 2010;31:6519-6529
  • Re F, Airoldi C, Zona C, Quattrocchi N, La Ferla B, Nicotra F, Masserini M. Beta Amyloid Aggregation Inhibitors: Small Molecules as Candidate Drugs for Therapy of Alzheimer Disease. Current Medicinal Chemistry 2010;17(27):2990-3006
  • Bulbarelli A, Lonati E, Cazzaniga E, Re F, Sesana MS, Barisani D, Sancini GA, Mutoh T, Masserini M. TrkA pathway activation induced by Amyloid-beta (Abeta). Molecular and Cellular Neurosciences 2009;40(3):365-373
  • Cazzaniga E, Bulbarelli A, Lonati E, Re F, Galimberti G, Gatti E, Pitto M, Ferrarese C, Masserini M. Enhanced folate binding of cultured fibroblasts from Alzheimer’s disease patients. Neuroscience Letters 2008;436(3):317-320
  • Sesana S, Re F*, Bulbarelli A, Salerno D, Cazzaniga E, Masserini M. Membrane features and activity of GPI-anchored enzymes: Alkaline phosphatase reconstituted in model membrane. Biochemistry 2008;47(19):5433-5440
  • Re F, Sesana S, Barbiroli A, Bonomi F, Cazzaniga E, Lonati E, Bulbarelli A, Masserini M. Prion protein structure is affected by pH-dependent interaction with membranes: A study in a model system.
  • Colombo, F. Corsi, D. Foschi, E. Mazzantini, S. Mazzucchelli, C. Morasso, E. Occhipinti, L. Polito, D. Prosperi, S. Ronchi, P. Verderio “HER2 targeting as a two-sided strategy for breast cancer diagnosis and treatment: outlook and recent implications in nanomedical approaches” Pharmacol. Res., 2010, 62, 150-165.
  • Re; I. Cambianica; S. Sesana; E. Salvati; A. Cagnotto; M. Salmona; P. Couraud; M.  Moghimi; M. Masserini; G. Sancini  Functionalization with ApoE-derived peptides enhances the interaction with brain capillary endothelial cells of nanoliposomes binding amyloid-beta peptide . Nanomedicine: Nanotechnology, Biology and Medicine , 2011, accepted
  • Pasqua L, Cundari S, Ceresa C, Cavaletti G. “Recent development, applications, and perspectives of mesoporous silica particles in medicine and biotechnology” Curr Med Chem. 2009, 16(23): 3054-63.
  • Cavaletti G, Cassetti A, Canta A, Galbiati S, Gilardini A, Oggioni N, Rodriguez-Menendez V, Fasano A, Liuzzi GM, Fattler U, Ries S, Nieland J, Riccio P, Haas H. “Cationic liposomes target sites of acute neuroinflammation in experimental autoimmune encephalomyelitis.” Mol Pharm. 2009 Sep-Oct, 6(5):1363-70
  • Orciani M, Cavaletti G, Fino V, Mattioli-Belmonte M, Tredici G, Bruni P, Di Primio R. “Exploiting CD38-mediated endocytosis for immunoliposome internalization.” Anticancer Drugs. 2008, Jul, 19(6):599-605
  • Erika Bereczki; Francesca Re,; Massimo E Masserini ; Bengt Winblad,,  Jin-Jing Pei, Liposomes functionalized with acidic lipids rescue Aβ-induced toxicity in murine neuroblastoma cells.   Nanomedicine: Nanotechnology, Biology and Medicine , 2011, accepted

3. Diagnostics

  • Snellman A, Rokka J, López-Picón FR, Helin S, Re F, Löyttyniemi E, Pihlaja R, Forloni G, Salmona M, Masserini M, Solin O, Rinne JO, Haaparanta-Solin M. Applicability of [¹¹C]PIB micro-PET imaging for in vivo follow-up of anti-amyloid treatment effects in APP23 mouse model. Neurobiology of Aging 2017;57:84-94
  • Rokka J, Snellman A, Kaasalainen M, Salonen J, Zona C, La Ferla B, Nicotra F, Re F, Masserini M, Forsback S, Lopez-Picon F, Rinne JO, Haaparanta-Solin M, Solin O. 18F-labeling syntheses and preclinical evaluation of functionalized nanoliposomes for Alzheimer’s disease. Eur J Pharm Sci. 2016;88:257-66.
  • Rokka J, Snellman A, Zona C, La Ferla B, Re F, Masserini M, Haaparanta M, Rinne J, Solin O. Synthesis of functionalized [F-18]liposomes for preclinical PET imaging in Alzheimer’s disease. J Label Compd Radiopharm 2013;56:385–391.
  • Kurkina T, Sundaram S, Sundaram RS, Re F, Masserini M, Kern K, Balasubramanian K. Self-assembled electrical biodetector based on reduced graphene oxide. ACS Nano 2012;6(6):5514-5520
  • Re F, Moresco RM, Masserini M. Nanoparticles for neuroimaging. Journal of Physics D: Applied Physics 2012;45(7),
  • Brambilla, R. Verpillot, M. Taverna, L. De Kimpe, B. Le Droumaguet, J. Nicolas, M. Canovi, M. Gobbi, F. Mantegazza, M. Salmona, V. Nicolas, W. Scheper, P. Couvreur, K. Andrieux, “New Method Based on Capillary Electrophoresis with Laser-Induced Fluorescence Detection (CE-LIF) to Monitor Interaction between Nanoparticles and the Amyloid-beta Peptide ” Analytical Chemistry, 2010, 82, 10083-10089
  • Piazza, M. Colombo, I. Zanoni, F. Granucci, P. Tortora, J. Weiss, T. Gioannini, D.Prosperi, F. Peri “Uniform LPS-loaded magnetic nanoparticles for the investigation of LPS/TLR4 signaling” Angew. Chem. Int. Ed., 2011, 50, 622-626.
  • Mazzucchelli, M. Colombo, C. De Palma, P. Verderio, M. D. Coghi, E. Clementi, P. Tortora, F. Corsi, D. Prosperi “Synthesis of single-domain protein A-engineered magnetic nanoparticles: toward a universal strategy to site-specific labeling of antibodies for targeted detection of tumor cells” ACS Nano, 2010, 4, 5693-5702
  • Cerofolini GF,  Amato  P,  Masserini M, Mauri G. “A surveillance system for early-stage diagnosis of endogenous diseases by swarms of nanobots” Advanced Science Letters, 2010, Vol. 3, 345–352
  • Sordan, R; Miranda, A; Traversi, Masserini M. et al “Vertical arrays of nanofluidic channels fabricated without nanolithography” Lab-on-Chip, 2009, 9 ,1556
  • Corsi, C. De Palma, M. Colombo, M. Nebuloni, S. Ronchi, G. Rizzi, R. Allevi, A. Tosoni, Trabucchi, E. Clementi, D. Prosperi “Towards ideal magnetofluorescent nanoparticles for bimodal detection of breast cancer Cells” Small, 2009, 5, 2555-2564.
  • Colombo, S. Ronchi, D. Monti, F. Corsi, E. Trabucchi, D. Prosperi “Femtomolar detection of auto-antibodies by magnetic relaxation nanosensors” Anal. Biochem., 2009, 392, 96-102.
  • Prosperi, C. Morasso, P. Tortora, D. Monti, T. Bellini “Avidin decorated core-shell nanoparticles for biorecognition studies by elastic light Scattering” ChemBioChem, 2007, 8, 1021-1028
  • Caccia M.; Sironi L.; Collini M.; Chirico G.; Zanoni I.; Granucci G. “Image Filtering for Two-photon Deep Imaging of Lymphonodes” Eur. Biophys. J., 2008, 37: 979-987

4. Nanobiophysics

  • Cristofalo, M., Kovari, D., Corti, R., Salerno, D., Cassina, V., Dunlap, D., Mantegazza, F. “Nanomechanics of Diaminopurine-Substituted DNA” Biophysical Journal, 116, 760-771, (2019)
  • Arenas-Guerrero, P., Delgado, A.V., Donovan, K.J., Scott, K., Bellini, T., Mantegazza, F., Jiménez, M.L. “Determination of the size distribution of non-spherical nanoparticles by electric birefringence-based methods” Scientific Reports, 8, 9502, (2018)
  • Misiak, M., Mantegazza, F., Beretta, G.L. “Methods for elucidation of DNA-anticancer drug interactions and their applications in the development of new drugs” Current Pharmaceutical Design, 22, 6596-6611, (2016)
  • Salerno, D., Beretta, G.L., Zanchetta, G., Brioschi, S., Cristofalo, M., Missana, N., Nardo, L., Cassina, V., Tempestini, A., Giovannoni, R., Cerrito, M.G., Zaffaroni, N., Bellini, T., Mantegazza, F. “Platinum-Based Drugs and DNA Interactions Studied by Single-Molecule and Bulk Measurements” Biophysical Journal, 110, 2151-2161, (2016)
  • Cassina, V., Manghi, M., Salerno, D., Tempestini,  A., Iadarola,  V., Nardo, L., Brioschi, S., Mantegazza,  F. “Effects of cytosine methylation on DNA morphology: an atomic force microscopy study” BBA – General Subjects 1860, 1-7, (2016)
  • Zanella, A., Castagna, L., Salerno, D., Scaravilli, V., El Sayed Deab, S.A.E.A., Magni, F., Giani, M., Mazzola, S., Albertini, M., Patroniti, N., Mantegazza, F., Pesenti, A. “Respiratory electrodialysis a novel, highly efficient extracorporeal CO2 removal technique” American Journal of Respiratory and Critical Care Medicine, 192, 719-726, (2015)
  • Salerno, D. Brogioli, V. Cassina, D. Turchi, G.L. Beretta, D. Seruggia, R. Ziano, F. Zunino, F. Mantegazza,  “Magnetic tweezers measurements of the nanomechanical properties of DNA in the presence of drugs.” Nucleic Acids Research, 2010, 38, 7089-7099
  • Salerno, D. Brogioli, V. Cassina, D. Turchi, G.L. Beretta, D. Seruggia, R. Ziano, F. Zunino, F. Mantegazza,  “Magnetic tweezers measurements of the nanomechanical properties of DNA in the presence of drugs.” Nucleic Acids Research, 2010, 38, 7089-7099
  • Sesana S, Re F, Bulbarelli A, Salerno D, Cazzaniga E, Masserini M. “Membrane features and activity of GPI-anchored enzymes: alkaline phosphatase reconstituted in model membranes” Biochemistry, 2008, 47, 5433-4
  • Re F, Sesana S, Barbiroli A, Bonomi F, Cazzaniga E, Lonati E, Bulbarelli A, Masserini M. “Prion protein structure is affected by pH-dependent interaction with membranes: A study in a model system” FEBS Lett., 2008, Vol. 582, pp.215-20
  • Cassina, D. Seruggia, G. L. Beretta, D. Salerno, D. Brogioli, S. Manzini, F. Zunino and F. Mantegazza “Atomic force microscopy study of DNA conformation in the presence of drugs ” European Biophysics Journal, 40, 59-68, (2010)
  • Gregori, V. Cassina, D. Brogioli, D. Salerno, L. De Kimpe, W. Scheper, M. Masserini and F. Mantegazza “Stability of A (1-42) peptide fibrils as consequence of environmental modifications”. European Biophysics Journal, 2010, 39, 1613-1623
  • Morasso, T. Bellini, D. Monti, M. Bassi, D. Prosperi, S. Riva “Dispersed Phantom Scatterer technique reveals subtle differences in substrate recognition by phospholipase D inactive mutants” ChemBioChem, 2009, 10, 639-644

5.Toxicology

  • Mantecca P, Farina F, Moschini E, Gallinotti D, Gualtieri M, Rohr A, Sancini G, Palestini P, Camatini M.“Comparative acute lung inflammation induced by atmospheric PM and size-fractionated tire particles” Toxicology  Letters, 2010, 198:244-254
  • Mantecca P, Sancini G, Moschini E, Farina F, Gualtieri M, Rohr A, Miserocchi G, Palestini P, Camatini M. “Lung toxicity induced by intratracheal instillation of size-fractionated tire particles” Toxicology Letters, 2009, 189(3):206-14.
  • Miserocchi, G. Sancini, F. Mantegazza F., G. Chiappino,  “Translocation pathways for inhaled asbestos fibers”, Environmental Health, 2008, 7
  • Beretta E., Gualtieri M., Botto L., Palestini P., Miserocchi G., and Camatini M. “Organic extract of tire debris causes localized damage in plasma membrane of human

Publications on Nanomedicine  related areas

  • Magni F, Van Der Burgt YE, Chinello C, Mainini V, Gianazza E, Deelder AM, Kienle MG “Biomarkers discovery by peptide and protein profiling in biological fluids based on functionalized magnetic beads purification and mass spectrometry”  Blood Transfus. 2010 Jun, 8 Suppl 3:s92-7.
  • La Ferla B., Zona C.,  Nicotra F. Easy silica gel supported desymmetrization of PEG SYNLETT, 2009, 14, 2325-2327.
  • La Ferla B., Russo L., Airoldi C., Nicotra F. “Solid-phase supported mimic of GDP-L-Galactose” Tetrahedron Asymm. 2009, 20, 744–745
  • Ceresa C, Cavaletti G. “Drug transporters in chemotherapy induced peripheral neurotoxicity: current knowledge and clinical implications” Curr Med Chem. 2011,18(3):329-41
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  • Gianazza E, Mainini  V, Castoldi G, Mauri G, Zoppis I, Magni F, Kienle MG “Different expression of Fibrinopeptide A and related fragments in serum of type 1 diabetic patients with nephropathy” of Proteomics. 2010 Jan 3;73(3):593-601.
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